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Rather, a growing body of evidence suggests that the systemic and local actions of incretins and metabolic hormones modulate multiple pathways that can promote inflammatory and fibrotic injury

The accumulation of calcium ions within cells can potentially induce the release of Cytochrome C (CytC) in mitochondria, which activates caspase-9 and the final executor protein caspase-3

This review provides a critical and translational analysis of GSH-responsive nanomedicine, highlighting chemical strategies such as disulfide/diselenide linkages, transition metal systems, and GSH-activated prodrugs

They are less toxic, biodegradable, and offer antioxidant, anti-inflammatory, and antimicrobial properties