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De Biase et al., Alcohol exposure sensitizes the activation of microglia through toll-like receptors (TLRs), purinergic P2X receptors (PRXR), and cytokine signaling (Crews et al., In vitro , a high dose of alcohol exposure induced increases in TLR4, TLR2, IL-1, TNF- , and inducible nitric oxide synthetase (iNOS) expression

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Discussion Creatine and GSH, two metabolites of glycine, are abundant in animal tissues and exert crucial physiological functions by supporting antioxidative capacity and energy metabolism [1]

Rehabilitation Cardiopulmonary Rehabilitation can improve cardiac and systemic dysfunction caused by cardiovascular diseases, solve residual disease problems after acute and severe diseases, prevent recurrence of cardiovascular events, and help patients return to a healthy life.