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In experimental animal models, FOXO4-DRI preferentially targets senescent cells while largely sparing healthy cells, although its safety and selectivity in humans remain unknown

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He and his team have worked to address maternal mortality through a care management program, which uses a population health approach to identify members early in pregnancy, calculate risk and address their needs through the first year after delivery

In addition to megaloblastic anaemia, the other classic pathophysiological manifestation of B12 deficiency is neuronal demyelination, which affects both the peripheral and central nervous systems [293] and shown in Figs 9 and 10