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Broadening horizons: research on ferroptosis in lung cancer and its potential therapeutic targets

The catabolism of NAD + , ADPR, and AMP to ADO was higher in samples from patients with severe MM than in those with MGUS and SMM ( These experiments lead to several key conclusions

These specific miRNAs, through the downregulation of MAT1A , lowered nuclear SAMe levels, leading to hypomethylation of the LIN28B promoter region and increased LIN28B expression[56]