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therefore, randomized controlled trials incorporating sham or intra-articular control groups and quantitative volumetric MRI assessment of BMLs are required to confirm efficacy and define optimal patient selection

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Option 1: Discard and mix fresh Cost: Price of new vial Benefit: Guaranteed full potency Risk: None (besides cost) Option 2: Continue using Cost: None (already paid for) Benefit: Don't waste remaining peptide Risk: 10-15% potency loss means 10-15% less effectiveness Calculation: If vial costs $50 and you're at day 35 with half remaining, you're deciding whether to waste $25 to guarantee full potency, or accept 10-15% reduced effectiveness

They are physically active adults who want to add lean tissue, reduce body fat, and improve overall body composition simultaneously