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doi:10.1136/jcp.42.6.624

Answer: After age 30, adults may lose between 3% to 8% muscle mass each decade, and the rate of muscle loss may accelerate after age 60 (Volpi, Curr Opin Clin Nutr Metab Care 2018)

Melanin is the pigment responsible for skin color, and its overproduction leads to darker skin tones and hyperpigmentation

Plant Physiol 140:613623 Smeets K, Opdenakker K, Remans T, van Sanden S, van Belleghem F, Semane B, Horemans N, Guisez Y, Vangronsveld J, Cuypers A (2009) Oxidative stress-related responses at transcriptional and enzymatic levels after exposure to Cd or Cu in a multipollution context