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Typische Anzeichen sind: Mdigkeit und Abgeschlagenheit Klteempfindlichkeit Gewichtszunahme trotz unvernderter Ernhrung Verstopfung Trockene Haut Stimmvernderungen Muskelschmerzen in den Beinen Gelenkschmerzen in den Fingern Oft sind die Beschwerden unspezifisch und variieren, abhngig von Alter , Geschlecht und individuellem Krankheitsverlauf , was die Diagnose anfangs erschweren kann

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Inhibition of ferroptosis underlies EGCG mediated protection against Parkinsons disease in a Drosophila model

5.2 Adverse effect profiles of medications While the efficacy of current first-line medications in the treatment of DPN has been affirmed, safety concerns have increasingly emerged, limiting their long-term use