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J Neurochem 73:390399 Kannan R, Yi JR, Tang D, Li Y, Zlokovic BV, Kaplowitz N (1996) Evidence for the existence of a sodium-dependent glutathione (GSH) transporter

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Studies have explored conjugating ferroptosis inducers, such as RSL3 prodrugs or GPX4-targeting siRNA, to HER2 antibodies or their fragments (e.g., scFv), to construct siRNAantibody fusion nanosystems capable of recognizing and binding to the surface of HER2-positive cells, thereby triggering endocytosis and targeted intracellular drug release