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Several functions that involve B Vitamins include: Metabolism (energy) Neurological function DNA production & repair Nerve and neurotransmitter function Digestion & appetite Hormone & cholesterol production Infection prevention Eye/vision health Blood cell production Cell growth & division B vitamins are crucial for energy and metabolism

This genetic metabolic block severely impairs the body's ability to produce cellular energy and clear out neurotoxins, directly contributing to the hallmark symptoms of ME/CFS, including profound post-exertional malaise (PEM) and unrefreshing sleep

[] Furthermore, BNIP3, a critical mitophagy receptor, is a known transcriptional target of FOXO3, which itself can stimulate PGC-1 expression

See a side-by-side comparison of Ozempic vs metformin here