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3 Potential link between gut microbiota metabolites and ITP Alterations in the gut microbiota can participate in the generation of the host immune system and in a range of inflammatory responses, and the metabolites produced by the gut microbiota, as the signaling molecules, can be seen as mediators of the interactions between the gut microbiota and their hosts

Production of L-Carnitine Production: Your body naturally produces L-carnitine, primarily in the liver and kidneys, from the amino acids lysine and methionine

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Notably, L-dopa impairs homocysteine metabolism and elimination, leading to hyperhomocysteinemia and associated disorders, as confirmed by a cohort study (Mller and Kuhn 2009)