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As a result, first-line options might prioritize antidepressants that are less dependent on CYP2D6 metabolism, such as escitalopram or sertraline (with careful consideration of CYP2C19 status), or non-SSRI agents like desvenlafaxine (Lense et al., 2024)

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Evidently, WS works as an immunomodulator that mitigates the airway overresponsiveness seen in mice asthmatic models suggesting that botanical drugs, like known adjuvants, can also modulate diseases in a favorable manner [48]