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2022;34(25):e2108360

Chait, A Anti-HMGB1 antibody reduces weight gain in mice fed a high-fat diet Nutr Diabetes 5 e161

Some of the observed changes in the immune and metabolic profiles persisted at the follow-up, suggesting a sustained impact from the short-term intervention

Therefore, hyperammonemic patients present potentially life-threatening neuropsychiatric symptoms, whose severity is related with the hyperammonemia magnitude and duration, as well as the brain maturation stage