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What lupus patients need is not broader suppression but smarter modulation, an approach that corrects specific immune imbalances without leaving the rest of the immune system compromised

Pharmacotherapy for generalized anxiety disorder in adult and pediatric patients: an evidence-based treatment review

Hum Mol Genet 23(4):980991 Herman DS, Lam L, Taylor MR, Wang L, Teekakirikul P, Christodoulou D, Conner L, DePalma SR, McDonough B, Sparks E, Teodorescu DL, Cirino AL, Banner NR, Pennell DJ, Graw S, Merlo M, Di Lenarda A, Sinagra G, Bos JM, Ackerman MJ, Mitchell RN, Murry CE, Lakdawala NK, Ho CY, Barton PJ, Cook SA, Mestroni L, Seidman JG, Seidman CE (2012) Truncations of titin causing dilated cardiomyopathy

The peptide stimulates 41 genes in the ubiquitin/proteasome system while suppressing only 1, indicating enhanced cellular "cleansing" capacity for removing damaged proteins