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In addition, the nongenetic surface modification of MSCs with sialyl Lewis X carbohydrate using a polyacrylamide linker and biotin/streptavidin interaction showed robust rolling on the endothelium and homed inflamed tissues in vivo more efficiently than unlabeled MSCs 46

(62, 63), piperine, an alkaloid found in black pepper, increases the plasma concentration of curcumin by up to 2000% by blocking intestinal and hepatic glucuronidation