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In all models, the following fixed covariates were entered: assigned treatment (investigational product or placebo), baseline measurement of the outcome of interest, visit (day 14 1 day or day 28 1 day), visit in interaction with treatment, period (period 1 or period 2), sex and, for MIDT outcomes, incentive level

HLA-DR reference range is under 25 %, however, we established a cut off level of 35 % to high level of expression, which was not achieved by all patients

Ethosome or Transfersome Cream (High Penetration, Less Common) Strong Choice Ethosomes (ethanol-enriched liposomes) show superior skin penetration versus conventional liposomes in comparative studies for small peptides

F.SegonzacC.WormitA.MadhouP.BennettM.et al