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Oxidative stress plays an important role in the pathogenesis of AD, with studies demonstrating elevated levels of PC in dry skin and AD skin lesions (56)

10.1634/stemcells.2005-0121 308 ZhuC.LiJ.LiuC.ZhouP.YangH.LiB

It is possible that this process is related to the different tumorigenic stages of cancer, and therefore with different microenvironment requirements for tumor progression or favoring certain cellular subsets (Gonzalez et al., 2018)