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co-stimulatory ligand includes a molecule on an antigen presenting cell e.g., an APC, dendritic cell, B cell, and the like) that specifically binds a cognate co-stimulatory molecule on a T cell, thereby providing a signal which, in addition to the primary signal provided by, for instance, binding of a TCR/CD3 complex with an MHC molecule loaded with peptide, mediates a T cell response, including, but not limited to, proliferation, activation, differentiation, and the like

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Adjunctive Host-Directed Therapy With Statins Improves Tuberculosis-Related Outcomes in Mice