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Berberine ameliorates iron levels and ferroptosis in the brain of 3 x Tg-AD mice

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PCS demonstrates extraordinary proficiency in activating renal inflammatory network architectures through complementary yet mechanistically distinct pathophysiological paradigms: it promotes ROS generation via NADPH oxidase activation cascades within renal tubular epithelial cellular matrices, simultaneously catalyzing JNK and p38 MAPK signaling pathway orchestration (Chang et al., 2020)