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Published online August 8, 2018 DOI: Abstract PDF Nonalcoholic fatty liver disease (NAFLD), together with metabolic syndrome and obesity, has shown a rapid increase in prevalence worldwide and is emerging as a major cause of chronic liver disease and liver transplantation

The liver tumor microenvironment (TME) consists of different cell populations including cancer cells, infiltrating immune cells, endothelial cells and cancer associated fibroblasts (CAFs)

When the connectivity scores were close to 1, the drugs were deemed to have strong potential to restore the normal gene expression profile of the PD-associated genes