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In this review, we will present the emerging antioxidant therapies in FRDA, those acting directly on ROS and those involved in the upregulation of antioxidant response elements and metabolic pathways in the mitochondria (Table 1)

10.13375/j.cnki.wcjps.2020.01.008 171 XieX.SongY.BiX.LiuX.XingY.CheZ

Studies have found that GSK3B deletion leaves HSCs in a precancerous state, and progression to acute myeloid leukaemia (AML) is facilitated after GSK3A deletion