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Why Botox for TMJ

A novel single nucleotide polymorphism in the 3 untranslated region of human glutathione peroxidase 4 influences lipoxygenase metabolism

To replenish intracellular GSH, cells synthesize GSH in a two-step metabolic pathway centred on the rate-limiting enzyme glutamate cysteine ligase (GCL), which is composed of a catalytic (GCLC) and a regulatory or modifier (GCLM) subunit, and the GSH synthetase (GS) 22