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The atomic coordinates of Cp1B with adenosine and MES, apo papain, papain with 1 , papain with E-64c, papain with E-64d and papain with (2 S ,3 S )- t -ES- a9 - b7 were deposited to the PDB under accession codes 9CJN, 9CLH, 9CKT, 9EG7, 9CKW and 9CKY, respectively

Concurrent mutations in STK11 and KEAP1 promote ferroptosis protection and SCD1 dependence in lung cancer

Preclinical and clinical studies have demonstrated that bioactive compounds such as polyphenols, alkaloids, terpenoids, saponins, and flavonoids exert beneficial effects on AD-related pathways by reducing oxidative stress, suppressing neuroinflammation, preventing A aggregation, and modulating tau hyperphosphorylation (Liu et al., 2024)