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Older adults also tend to have less muscle mass and body water, leading to higher blood alcohol content from the same amount of alcohol compared to younger people

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Ability of Cyclodextrin to Form Inclusion Complexes Cyclodextrins have relatively hydrophobic inner cavities and a hydrophilic outer surface covered with hydroxyl groups

Therefore, a phase I clinical trial using a combination of olaparib with navitoclax, an inhibitor of Bcl-2/Bcl-XL, in patients with high-grade serous carcinoma and triple-negative breast cancer is currently active (NCT05358639, ClinicalTrials.gov, 2025)