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Modules correlated with the KO genotype were enriched for neuronal and synaptic genes involved in vesicle-mediated transport, neurotransmitter secretion, and GTPase activity, suggesting that RAMP deletion disrupts synaptic signaling networks critical for metabolic regulation [2]

TPPU and TPPU + DHA Protect Hippocampal Neurons in Diabetes H&E staining of the CA1 region of hippocampus from normal healthy rat revealed regularly arranged neurons with large, round, transparent, and intact nuclei

The FDA classifies it as a Category 2 bulk drug substance

Read review Dihexa for Tinnitus & Hyperacusis Lenire neuromodulation, Susan Shore Auricle, cochlear synaptopathy, and the 7.6 million UK tinnitus population