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Glutathione does not permanently alter melanin production

The primary outcome measure in TRANSEURO is the change of MDS-UPDRS part 3 score at 36 months post transplantation and change in F-DOPA-PET is included in the secondary end-points

Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors

In the case of immune cells, this results in attenuated surveillance and immune evasion, whereas in stromal cells it may lead to maladaptive metabolic reprogramming [370, 451]