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Long-term dopaminergic replacement frequently leads to end-of-dose deterioration and motor complications (5, 6), while rivastigmine may provoke nausea, vomiting, and tremor (7)

While mammals carry eight genes encoding canonical GPX, proteins such as GST [26] and peroxiredoxin [27] also show GSH-dependent peroxidase activity to some extent

Beyond this window, oxidation converts reduced glutathione (GSH) to its inactive form (GSSG) at accelerating rates, stripping the molecule of its electron-donating antioxidant capacity

Br J Nutr 80: 5155, 1998 [DOI] [PubMed] [Google Scholar] 54.Orlowski M, Meister A: Partial reactions catalyzed by gamma-glutamylcysteine synthetase and evidence for an activated glutamate intermediate