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In recent years, epigenetic regulation has emerged as a central mechanism linking these pathological processes, mediating persistent alterations in gene expression during DKD progression [6, 7]

Protective effects of sulforaphane in experimental vascular cognitive impairment: contribution of the Nrf2 pathway

doi: 10.1007/s12264-020-00620-5 13 ChenG

However, sortilin binds to numerous ligands and plays a major role in mannose 6-phosphate receptor-independent transport of lysosomal hydrolases utilizing motifs in the intracellular domain that mediate trafficking from the Golgi and late endosomes