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Purushothuman S, Nandasena C, Peoples CL, El Massri N, Johnstone DM, Mitrofanis J, Stone J

Antimicrob Agents Chemother 47 (12), 37993805

To confirm the direct binding of iMQT_020 to SLC1A5_var, microscale thermophoresis (MST) was performed using purified eGFP-tagged SLC1A5_var WT and FIL/AAA proteins

Simultaneously, anti-inflammatory cytokines such as TGF-, GDF-5, GDF-6, IL-4, and IL-10 are also present in the degenerative environment and can, to some extent, delay degeneration and alleviate pain (Wang et al., 2016), with their balance potentially closely related to the polarization state of macrophages (Yamamoto et al., 2022