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Description

Unformulated curcumin has an oral bioavailability of less than 1%

The experimental design for fasting and refeeding is illustrated in Supplementary Fig

Astrocytes, positioned at the interface between the brain parenchyma and the perivascular space, which includes capillaries, larger arteries, and veins [66], play a role in the removal of A from the brain via mechanisms that include enzymatic degradation of A and the upregulation of efflux transporters for A at the BBB [67]