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The cholinergic-anti-inflammatory pathway is the efferent arm of the inflammatory reflex, which mediates the prevention of systemic inflammation by stimulating the vagus nerve (88)

Depending on your case, your healthcare professional will do so

The lipid peroxidation end product 4 - hydroxy - 2, 3-nonenal up-regulates transforming growth factor beta1 expression in the macrophage lineage: a link between oxidative injury and fibrosclerosis