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van den Beld and colleagues 27 showed that higher serum IGFBP-2 levels were associated with a higher degree of disability and a lower physical performance, muscle strength, and bone mineral density of proximal femur

Mithal A, Kifor O, Kifor I, Vassilev P, Butters R, Krapcho K, Simin R, Fuller F, Hebert SC, Brown EM

Additionally, in pyrimidine synthesis, the conversion of uridine monophosphate (UMP, the primary precursor) takes place, leading to the formation of deoxyuridine monophosphate (dUMP)