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5mg in 3ml (1.67mg/ml concentration) Maximum precision for dose measurement, but injection volumes become large at higher doses

Peripheral and central inflammation may be linked through the ability of systemic inflammatory mediators to travel through a leaky BBB, as UPFs have previously been shown to compromise BBB integrity (117)

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The rate of DCF formation indicative of intracellular ROS levels can be quantified through fluorometry or fluorescence microscopy ( 2 ), resulting in the formation of a blue or purple formazan precipitate that marks superoxide accumulation