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This is supported at least in part at the biochemical level: the Km of L-cysteinyl-tRNA synthetase towards cysteine, which directs cysteine to translational machinery, is less than one tenth of that for other enzymes of cysteine metabolism such as GCS or cysteine dioxygenase 22

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Vitamin C to Support the Three Active Compounds Vitamin C plays a multifaceted role in supporting glutathione function

Regarding the systemic toxicity of the treatments, we observed no unusual changes in the body weight of the mice during the observation period and no significant differences in the body weight at the end of the observations, right before sacrificing them (Supplementary Fig