glutathione skin whitening review as a skin‐lightening agent and in melasma: a systematic - Sarkar - 2025 - International Journal of Dermatology Honest Review Zuwacosmetics Glutathione Whitening

In the cardiovascular system, Mg 2+ promotes the release of NF-B through its antioxidant effect by eliminating ROS, impacting downstream inflammatory signaling pathways, and regulating inflammation

Cysteine is often a limiting factor to GSH production, therefore, supplementing with L-cysteine can be used to improve GSH status in the body and has also been associated with lower levels of inflammation and insulin resistance

Juglanin treatment significantly reduced Sting expression, ameliorating TGF--induced collagen accumulation and highlighting its potential application in treating fibrotic diseases ( 3.2.2 Saponins and alkaloids -carboline alkaloids, extracted from Snow Fungus, exhibit anti-inflammatory effects by inhibiting the secretion of cytokines MCP-1, IL-6, TNF-, and IL-1 in LPS-induced RAW264.7 cells, thereby mitigating inflammation ( Lycorine (LYC), an alkaloid from Amaryllidaceae plants, significantly reduced alveolar collapse and collagen accumulation in bleomycin-induced pulmonary fibrosis in mice, lowering fibrosis marker levels including hydroxyproline (HYP)

Skin elasticity will increase due to enhanced levels of collagen leading to an improved appearance with fewer signs of aging