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Nature 90 457465 Aspinwall R, Rothwell DG, Roldan-Arjona T, Anselmino C, Ward CJ, Cheadle JP, Sampson JR, Lindahl T, et al

Arachidonic acid is released from cellular phospholipids by the enzyme phospholipase A 2 (Fig

10.1002/adhm.202100683 Summary Keywords system Xc -/GSH/GPX4 axis, ferroptosis, drug resistance, solid tumor, therapy Citation Li F-J, Long H-Z, Zhou Z-W, Luo H-Y, Xu S-G and Gao L-C (2022) System X c /GSH/GPX4 axis : An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy