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Mature RBCs, which lack nuclei and organelles, are particularly dependent on the pentose phosphate pathway because it is the only mechanism for them to generate NADPH

Some may decide to settle after experiencing the locale, but most are likely to pass through and move on, either back from whence they came or on to another temporary haunt

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Unfortunately, patients often meet the KCC and lactate criteria quite late in the course of the disease, so these criteria are not useful as early predictors or as standards for transfer to a facility that performs the hepatic transplant