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In considering the results of epidemiological studies, it should be considered that systemic compensation (homeostasis) could be acting to counter the biochemical effect of the toxic agent(s) [31]

Given the functional role of SLC6A14 in extending the range of amino acid uptake (including glutamine and leucine, both of which are activators of mTORC1), as well as providing substrates for SLC1A5 and SLC7A5, the molecule has attracted much attention 99,100

Interaction between the PPAR pathway and the enzymes CYP4A and CYP2E1 has been described (Ip et al

1 Introduction Cisplatin combination therapy is a primary approach for solid malignancies ( Excessive oxidative stress is a pivotal contributor to cisplatin-induced nephrotoxicity, with the proximal tubule being the primary target (Zhang et al., 2024)