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Kuhn 2010)

Typically, NMN is converted into NAD + via NMN adenylate transferase (NMNAT), which plays a key role in biological regulation and is an important therapeutic target (Fig

For example, astrocytes have pivotal roles in brain energy metabolism [14,15,16,17], in the regulation of the extracellular milieu [13, 18], in the defence against reactive oxygen species and toxins [19,20,21], in neurotransmitter metabolism and neurotransmission [22,23,24,25] as well as in cognitive processes and memory formation [26,27,28,29]