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Intravenous administration of the extract Eruca sativa Mill [Brassicaceae] significantly reduced mean arterial pressure in both normotensive and hypertensive rats, with the antihypertensive effect being mediated by muscarinic receptors linked to NO release

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In brief, blood was drawn by median cubital vein venipuncture from healthy volunteers and centrifuged through a Ficoll Histopaque 1077 gradient (Sigma) to isolate mononuclear cells