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Specifically, murine systems lack the heterogeneous donor-recipient interactions, comorbidities (e.g., diabetes, hypertension), and immunosuppressive drug effects pervasive in clinical settings

and J.M

[DOI] [PubMed] [Google Scholar] [30].Luhby AL, Cooperman JM, Pesci-Bourel A

Despite its potential, the commercial adoption of Portulaca faces several challenges, such as low yields of bioactive compounds, scalability issues, and regulatory barriers