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Ectopic cellular expression of PGC-1 is shown to improve survival during oxidative stress conditions

Recent technological developments in these areas enable high-throughput analysis of thousands of metabolites and proteins from a variety of biological samples and model systems, that provides a powerful approach to unraveling the metabolic phenotypes associated with these complex diseases

Venigalla M, Gyengesi E, Mnch G

Combined with our previous findings, it can be concluded that bone homeostasis affects bone metabolism and is influenced by mitochondrial dysfunction and that the role of the Sirtuin family in bone homeostasis is progressively being appreciated