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This cascade activates caspase-8 and downstream caspase-3 (Takahashi et al., 1999), leading to DNA fragmentation and keratinocyte apoptosis (Simon et al., 2006)

In the liver, it has a G of 17.6 kJ/mol (4.21 kcal/mol), and it is highly allosterically regulated

The transcripts of APX1 in Ipomoea batata were detected clearly in leaves, weakly in stems, and not in non-storage and storage roots

41% of mAb products approved between 2015 and 2023 are administered by SC injection, whereas it was 24% between 1994 and 2014. About 79 mAb products, excluding antibody-drug conjugates (ADCs), were approved between 2015 and 2023, which is twice the number of products approved between 1994 and 2014 (31 products)