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Finally, based on the mechanistic insights gained from this study, BSO may serve as an effective adjuvant when combined with other ferroptosis inducers, such as glutamate, erastin or RSL3, to enhance ferroptotic cell death, a strategy that may hold promise for the rational design of ferroptosis-based anticancer therapies

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Both methods rely on binding of the polynucleotide to a complementary DNA or RNA

A: Visible changes can occur after the first use, with more significant results typically observed within a few days to weeks of consistent use