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Since miR-107 is downregulated in cell lines with mutated p53 (447), p53 mutations and accumulation of A may result in the decrease of miR-107 levels in AD patients

Barbalace MC, Talotta R, Rapisarda F, DAmico V, Lagan M, Malaguti M et al (2025) Unlocking the Power of the Mediterranean Diet: Two in One-Dual Benefits for Rheumatic and Thyroid Autoimmune Diseases

Low levels of GH and IGF-1 have been associated in different cohorts with endothelial dysfunction, increase in carotid intima-media thickness (CIMT), impaired coronary blood flow, coronary artery disease, congestive heart failure, left ventricular hypertrophy, arterial hypertension, myocardial infarction, and ischemic stroke ( 3 GH deficiency in adults In adults, HGH deficiency is associated with changes in body composition, including reduced lean body tissue, skeletal and myocardial muscle, increased total and trunk fat mass (FM), osteopenia or osteoporosis, and dry, thin, wrinkled skin

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