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Inhibition of SIRT1 expression resulted in increased NLRP3 activation and nuclear accumulation of PKM2, therefore, preventing the anti-inflammatory effects of quercetin

The efficacy of drugs in patients with chronic myeloid leukemia (CML) has also been measured through FRET-based biosensor-mediated monitoring of the activity of BCR-ABL kinase that is causatively expressed in CML patients 20