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Supplements taken orally, such as capsules and tablets, are the most common type, but their main disadvantage is their presumed ineffectiveness.

The same 4 mg daily sublingual dose will produce different circulating drug concentrations in a 150-pound person versus a 300-pound person due to differences in volume of distribution

BMC Pregnancy and Childbirth (2025) 25:1120 Table 2 Ovarian stimulation characteristics and pregnancy outcomes Low Average High P value Dosage of Gn (IU) 2646.43 933.92 2325.44 867.31&1 2353.34 885.07&2 0.01 Duration of Gn (days) 11.69 1.65 11.50 1.85 11.54 1.57 0.661 FSH value on trigger day (mIU/mL) 16.45 5.95 15.21 4.55 15.74 6.07 0.236 E2 value on trigger day (pg/ml) 2172.06 965.30 2272.20 980.56 2526.51 1202.85 0.068 LH value on trigger day (mIU/mL) 0.93 0.49 0.89 0.42 1.00 0.54 0.267 P value on trigger day (ng/ml) 0.68 0.37 0.76 0.43 0.77 0.38 0.186 No