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FUT2 promotes colorectal cancer metastasis by reprogramming fatty acid metabolism via YAP/TAZ signaling and SREBP-1

But its not just about gut health

Over time, mitochondrial damage accumulates, impairing their efficiency and releasing DAMPs into the cellular environment, which further stimulates inflammatory signalling, creating a selfperpetuating loop of mitochondrial dysfunction and OS, ultimately impairing energydependent wound repair processes such as cell migration and matrix deposition [52]

In PD, -syn aggregates also stimulate NLRP3 activation through mitochondrial stress and mtDNA release, exacerbating dopaminergic neuron degeneration [113, 114]