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Cells were then centrifuged at 16,000 g for 10 min at 4 C and the supernatant was transferred to liquid chromatography-mass spectrometry (LC-MS) glass vials

This reactive stroma substantially modifies the mechanical and biochemical properties of the TME, creating a favorable condition that supports tumor growth and immune evasion

In this paradigm, aquaporin 8 silencing, which is specifically expressed in IMM, enhances mitochondrial ROS generation and results in mitochondrial depolarization and cell death (Marchissio et al., 2012)

[DOI] [PubMed] [Google Scholar] 44.Betten DP, Cantrell FL, Thomas SC, Williams SR, Clark RF