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The experiments were approved by the Italian Ministry of Health (Rome, Italy) and performed in agreement with the ARRIVE (Animals in Research: Reporting in vivo Experiments) guideline (44), the guidelines of the Italian Ministry of Health (D.L

I Filip reports payment or honoraria for lectures, presentations, speakers bureaus, manuscript writing or educational events from Avicenna Medical and Clinical Research Institute

NIES39_A07680 co-purified with PilQ, and its high-confidence AlphaFold-predicted structure aligns well with the large lower ring part of the isolated nozzle complexes, a feature absent in other secretins (Figs

Glutathione modulates this pathway in multiple ways: it can shift melanin production toward the lighter pheomelanin, it interacts with intermediate molecules in the melanin pathway, and it helps maintain redox balance that affects enzyme activity inside melanosomes