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This conformational change further transduces through F279 6.51 and H280 6.52 to cause rearrangement of an aromatic cluster formed by residues W276 6.48 , F279 6.51 , H280 6.52 , and F312 7.42 (Fig

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At the same time, in a rat diabetes model an increased expression of Grx1 gene was revealed, this facilitating the translocation of NF-B into the nucleus and activation of cell adhesion molecules ICAM-1

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